Mariana trench-derived fungal polysaccharide AVP214–1 inhibits Singapore grouper iridovirus infection in vitro and in vivo

Key Points

• The polysaccharide AVP214–1 significantly reduces iridovirus infection in both in vitro and in vivo settings.
• In vitro results demonstrated a 70% decrease in viral load with AVP214–1 treatment.
• The approach involved experimental infection of the Singapore grouper with iridovirus after polysaccharide exposure.
• Findings suggest that AVP214–1 may serve as a potential antiviral treatment in aquaculture, though further research is needed.