Comparison of 2005 and 2024 diagnostic criteria for early identification of pediatric sepsis and septic shock in PICU patients: a prospective cohort study

Key Points

• Improved specificity under 2024 criteria may delay early diagnosis and treatment of septic shock.
• 2024 diagnostic criteria focus on strict definitions of septic shock, impacting timely patient care.
• Observational analysis of pediatric patients suggests a need for prospective studies to enhance early identification.
• AI-supported early warning models are essential in addressing diagnostic limitations for pediatric sepsis.