Anti-phospholipid antibodies as a risk factor for renal injury in patients with systemic lupus erythematosus: a comprehensive analysis

Key Points

• Anti-phospholipid antibodies significantly increase the risk of renal injury in systemic lupus erythematosus patients.
• Specifically, lupus anticoagulant and anticardiolipin antibodies drive this increased risk.
• Observational analysis found a strong association between seropositivity for aPL and renal complications.
• These findings highlight the need for monitoring antiphospholipid antibody levels to manage renal health in lupus patients.