Sustainable spectrofluorimetric determination of berberine in dietary supplements via Erythrosin B Ion-Pair complexation with mechanistic investigation, Box-Behnken optimization, and green chemistry assessment | Synapse
March 3, 2026Open Access
Sustainable spectrofluorimetric determination of berberine in dietary supplements via Erythrosin B Ion-Pair complexation with mechanistic investigation, Box-Behnken optimization, and green chemistry assessment
Key Points
Berberine detection is possible with a limit of detection at 0.01 mg/L, enabling precise measurement for dietary supplements.
The study used Box-Behnken optimization to enhance sensitivity and accuracy in detecting berberine via ion-pair complexation.
Spectrofluorimetric analysis incorporated green chemistry principles, promoting environmentally friendly practices in chemical analysis.
Results highlight the potential for sustainable testing methods that reduce harmful waste by using less toxic reagents.