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March 3, 2026
Tecovirimat hepatotoxicity in a man with Mpox infection
DR
Diana Ruiz-Cabrera
FM
Francisco Montoya
JS
Joaquín Sáez-Peñataro
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Key Points
Hepatotoxicity occurred after tecovirimat administration, indicating a possible adverse effect.
The patient experienced significant liver enzyme elevation, particularly alanine aminotransferase (ALT) levels.
Assessment based on clinical observations and laboratory tests suggested a direct link to tecovirimat.
Warning of potential risks underscores the need for careful monitoring during treatment with viral therapies.
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Ruiz-Cabrera et al. (Sun,) studied this question.
synapsesocial.com/papers/69a766ddbadf0bb9e87deb31
https://doi.org/https://doi.org/10.1016/j.eimce.2026.503030
Tecovirimat hepatotoxicity in a man with Mpox infection | Synapse