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Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3 | Synapse
March 3, 2026
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Cagrilintide lowers bodyweight through brain amylin receptors 1 and 3
AC
Alexandra Oliveira Carvas
University of Zurich
AL
Andrea S. Leuthardt
University of Zurich
PK
Patricia Kulka
University of Zurich
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Key Points
Cagrilintide significantly reduces bodyweight by targeting brain amylin receptors 1 and 3, enhancing energy metabolism.
An observed reduction of body weight highlights its influence in appetite regulation and energy balance over time.
Assessment using both biochemical analysis and behavioral tests validates the effects of cagrilintide on bodyweight management.
Further studies are necessary to explore long-term effects and optimal dosing strategies in diverse populations.
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Carvas et al. (Fri,) studied this question.
synapsesocial.com/papers/69a766e3badf0bb9e87decca
https://doi.org/https://doi.org/10.5167/uzh-290777