Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups
Key Points
Youth with internalizing disorders show distinct alterations in brain structure compared to those with externalizing disorders.
Findings indicate that major depressive disorder and ADHD impact brain structure uniquely, with observed variations in specific regions.
Analysis from the ENIGMA working groups highlights significant findings from multiple large-scale neuroimaging datasets.
Understanding these differences may improve treatment strategies and support targeted interventions for these disorders.
Shared and Distinct Alterations in Brain Structure of Youth With Internalizing or Externalizing Disorders: Findings From the ENIGMA Antisocial Behavior, ADHD, Major Depressive Disorder, and Anxiety Working Groups | Synapse