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March 3, 2026
IgM-enriched immunoglobulin treatment significantly improves coagulation dysbalance in an experimental animal model of fulminant sepsis
ID
Ildikó Beke Debreceni
University of Debrecen
BK
Bálint Krajcsir
University of Debrecen
ÁM
Ádám Attila Mátrai
University of Debrecen
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Key Points
Improved coagulation dysbalance is observed with IgM-enriched immunoglobulin treatment in sepsis.
The treatment resulted in significant improvements, with a notable reduction in coagulation abnormalities.
Experimental model assessments reveal beneficial effects on hemostatic parameters and infectious complications.
Potential implications for using IgM-enriched immunoglobulin as a treatment in severe sepsis cases.
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Debreceni et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76732badf0bb9e87dff5c
https://doi.org/https://doi.org/10.1016/j.thromres.2026.109607
IgM-enriched immunoglobulin treatment significantly improves coagulation dysbalance in an experimental animal model of fulminant sepsis | Synapse