Leukocyte-epithelial physical contacts mediate interstitial migration in vivo

Key Points

• Interstitial migration is significantly influenced by leukocyte-epithelial physical contacts, enhancing cell movement.
• Key evidence shows that these interactions contribute to effective tissue infiltration and immune response.
• Observational analysis of in vivo cellular interactions highlights the dynamic behavior of leukocytes during migration.
• This work suggests a vital role for cellular contacts in immune functions, emphasizing the need for further studies.