Geum japonicum Thunb. var. Chinese-P.decorata H.Andres herbal pair ameliorates CIRI-induced neuronal injury by facilitating mitochondrial transfer via the CD38/Miro1 signaling pathway | Synapse
March 3, 2026
Geum japonicum Thunb. var. Chinese-P.decorata H.Andres herbal pair ameliorates CIRI-induced neuronal injury by facilitating mitochondrial transfer via the CD38/Miro1 signaling pathway
Key Points
Mitochondrial transfer significantly reduces neuronal injury associated with CIRI, highlighting its protective role.
The CD38/Miro1 signaling pathway is crucial for the facilitated mitochondrial transfer observed in the study.
Assessment involved both in vitro and in vivo approaches to ensure consistency and robustness in findings.
These findings suggest Geum japonicum could offer new avenues for treating neuronal injuries.