March 3, 2026Open Access

Risk factors and a nomogram for bovine jugular vein conduit failure after right ventricular outflow tract reconstruction: a 10-year single-center cohort

Key Points

The nomogram estimates the risk of bovine jugular vein conduit failure based on peri-operative variables.
Model performance shows good internal validity but necessitates prospective multicenter validation.
Developed using a single-center cohort, the analysis highlights limitations in generalizability and event numbers.
Potential recalibration may enhance clinical implementation for patient-specific surveillance plans.

Abstract

Using routinely available peri-operative variables, we developed an interpretable nomogram to estimate the risk of BJVC failure and to inform individualized surveillance and intervention planning. The model showed good internal performance but was derived in a single-center cohort with a modest number of events; prospective multicenter validation and, if necessary, recalibration are required before routine clinical implementation.

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Cite This Study

Chen et al. (Fri,) studied this question.

synapsesocial.com/papers/69a767c2badf0bb9e87e23cb https://doi.org/https://doi.org/10.3389/fped.2026.1733522

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