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NAD boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice | Synapse
March 3, 2026
Open Access
NAD boosting increases atherosclerotic plaques and inflammation in Apoe knockout mice
YW
Yu-Jen Wang
University Hospital of Zurich
DG
Daniel S. Gaul
University of Zurich
EG
Era Gorica
Heart Failure & Transplant
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Key Points
Increased atherosclerotic plaques were observed, suggesting a potential link to cardiovascular issues.
Inflammation levels notably rose alongside increased atherosclerotic plaques in the model.
Assessment involved Apoe knockout mice to investigate the effects of NAD boosting.
These findings highlight the need for caution regarding NAD boosting interventions in cardiovascular health.
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Wang et al. (Thu,) studied this question.
synapsesocial.com/papers/69a767c5badf0bb9e87e240e
https://doi.org/https://doi.org/10.5167/uzh-290466
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