The orphan receptor GPR88 controls impulsivity and is a risk factor for Attention-Deficit/Hyperactivity Disorder.

Key Points

• Impulsivity is significantly influenced by GPR88, indicating its potential role in attention-deficit/hyperactivity disorder (ADHD).
• Changes in neurotransmission related to GPR88 were measured, revealing notable behavioral traits linked to impulsivity.
• Assessment involved behavioral analysis across ADHD-affected individuals and emphasized GPR88's importance in impulsive behaviors.
• Understanding GPR88's function could lead to new insights into ADHD, highlighting a possible therapeutic target in future research.