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March 3, 2026
The biological activity of recent metal complexes with pyrazole-based polydentate ligands
MZ
Małgorzata Zienkiewicz‐Machnik
Institute of Physical Chemistry
AG
Agnieszka Gilewska
Jan Kochanowski University
JM
Joanna Masternak
Jan Kochanowski University
Key Points
Biological activity was enhanced in metal complexes, notably affecting cellular processes and functions.
Key metrics highlighted include increased efficacy of pyrazole ligands with different metal ions, revealing potential targets.
Analysis of ligand coordination dynamics in various metal complexes provided insights into their mechanisms of action.
These findings may enable the development of novel therapeutic agents based on the novel metal complexes studied.
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Zienkiewicz‐Machnik et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76805badf0bb9e87e34ed
https://doi.org/https://doi.org/10.1016/j.inoche.2026.116312
The biological activity of recent metal complexes with pyrazole-based polydentate ligands | Synapse