Resveratrol effectively reduces nephrotoxicity caused by colistin treatment, highlighting its protective properties.
Colistin administration leads to increased markers of nephrotoxicity, with significant reductions observed when resveratrol is included in the treatment regimen.
This analysis focuses on regulating the nrf2 pathway and inhibiting ferroptosis as potential mechanisms of action for resveratrol.
Understanding these mechanisms may provide avenues for therapeutic strategies against antibiotic-induced kidney damage.