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Model-informed precision dosing of paroxetine to optimize individualized therapy in patients with mental disorders | Synapse
March 3, 2026
Model-informed precision dosing of paroxetine to optimize individualized therapy in patients with mental disorders
WH
Wanting Huang
ZW
Zhanzhang Wang
HX
Hui Xia
Guangzhou Psychiatric Hospital
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Key Points
Optimized individualized therapy leads to better management of symptoms in mental disorders, enhancing patient outcomes.
A significant finding reveals over 70% improvement in therapeutic response to paroxetine with precise dosing strategies.
This analysis utilizes model-informed dosing approaches to tailor paroxetine treatment based on individual patient characteristics.
Results emphasize the potential for model-informed precision dosing in enhancing mental health interventions.
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Huang et al. (Fri,) studied this question.
synapsesocial.com/papers/69a7689dbadf0bb9e87e54fb
https://doi.org/https://doi.org/10.1016/j.jad.2026.121168