Pheochromocytoma is a catecholamine-secreting neuroendocrine tumor originating in the adrenal medulla. In patients with pheochromocytoma, paroxysmal over-secretion of catecholamines can be triggered by various medications, including the commonly used antiemetic metoclopramide. We report herein a fatal case of pheochromocytoma crisis triggered by metoclopramide and present a literature review of metoclopramide-induced pheochromocytoma crises to elucidate their clinical characteristics.
Yamanashi et al. (Sun,) studied this question.