What question did this study set out to answer?

To investigate the effectiveness of CL-EVLPs in promoting corneal repair and restoring ocular surface homeostasis.

March 5, 2026Investigative Ophthalmology & Visual Science0 citationsOpen Access

CL-EVLPs Promote Corneal Repair in a BAC-Induced Corneal Injury Model via Ocular Microenvironment Reconstruction

MFMengjun FuTwitter (United States)DPDewei PengTwitter (United States)YXYijie XuTwitter (United States)

Key Points

To investigate the effectiveness of CL-EVLPs in promoting corneal repair and restoring ocular surface homeostasis.
Utilized a BAC-induced corneal injury model.
Administered CL-EVLPs to assess their impact on corneal epithelial regeneration.
Evaluated neural repair in the ocular surface microenvironment.
CL-EVLPs significantly enhanced corneal epithelial regeneration.
Restoration of ocular surface homeostasis was observed.
Demonstrated potential for safer and more economical ocular treatments.

Abstract

CL-EVLPs represent a novel natural nanobiologic that restores ocular surface homeostasis, effectively enhancing corneal epithelial regeneration and neural repair in the ocular surface microenvironment. This study provides a foundation for the development of plant-derived EVLPs as a safer and more economical therapeutic strategy for ocular surface disorders.

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