Expanding the Motor Band Sign in Motor Neuron Disease Using 7T MRI: Visualization of Cortical Layer-Dependent Iron Deposition in the Primary Motor Cortex.

Key Points

• This research aims to identify specific iron deposition patterns in the primary motor cortex of individuals with motor neuron disease using high-resolution 7T MRI.
• Utilized 7T MRI to visualize the motor cortex
• Analyzed the trilaminar appearance of cortical layers
• Compared findings with established clinical evaluations
• Identified a distinct trilaminar appearance in the motor cortex specific to motor neuron disease
• Demonstrated that 7T MRI can effectively visualize iron deposition patterns
• Established the motor band sign as a sensitive marker for motor neuron disease