ABSTRACT In this paper, we present a novel plasma‐based synthesis method for copper oxide nanoparticles (Cu₂O/CuO) employing a microsecond discharge in a liquid medium with copper granules positioned within the interelectrode space. The analysis revealed distinct morphological differences between the two phases: Cu₂O nanoparticles exhibited spherical and cubic shapes with an average size of 100 nm, while CuO nanoparticles displayed a flake‐like morphology with an average size of 450 nm. The synthesis process demonstrated a production rate of 50 mg/min with an energy efficiency of 16 μg/J. The best performance results were achieved at a Cu₂O nanoparticle concentration of 300 mg/mL. At this concentration, the synthesized nanoparticles exhibited antibacterial efficacy and cytotoxicity levels comparable to those produced by well‐established conventional techniques.
Zakletskii et al. (Sun,) studied this question.