Migraines and the association of cognitive impairment: a one- and two-sample mendelian randomization analysis

Key Points

• To examine the causal relationship between migraines and cognitive impairment using mendelian randomization.
• Conducted one- and two-sample mendelian randomization analyses
• Analyzed genetic variants associated with migraines
• Assessed cognitive impairment based on genetic data
• Found a significant causal association between migraines and cognitive impairment
• Indicators suggest that individuals with migraines show heightened cognitive impairment