One lineage, many diseases: γδ T cells as context‐dependent immune surveyors

Key Points

• The aim is to explore the diverse roles of γδ T cells in different disease contexts and their interactions with stress factors.
• Review of studies focusing on γδ T cell functions in infection, inflammation, and allergy.
• Analysis of the impact of cellular and metabolic stress on γδ T cells.
• γδ T cells show varied immune response depending on contextual factors.
• Cellular and metabolic stresses influence the effectiveness of γδ T cells in disease scenarios.