This research investigates how cumulative low-density lipoprotein cholesterol (LDL-C) levels affect the risk of end-stage renal disease (ESRD) in patients with type 2 diabetes.
Analyzed the relationship between cumulative LDL-C levels and ESRD risk
Focused on Korean patients with type 2 diabetes
Considered factors like duration of diabetes and number of antidiabetic medications
Found a higher risk of ESRD with increasing cumulative LDL-C levels
Notably higher risk was observed in patients taking multiple antidiabetic medications
Longer duration of diabetes was associated with a greater impact of LDL-C on ESRD risk
Abstract
ESRD risk increased with high cumulative LDL-C levels. This difference was more pronounced in patients with diabetes taking multiple antidiabetic medications and in those with a longer duration of diabetes.