Ayurveda describes the human body as an intricate network of channels known as Srotas, which are responsible for the transport, transformation, and nourishment of bodily tissues. The proper functioning of these channels is essential for maintaining physiological homeostasis. Classical Ayurvedic texts emphasize that disturbance of Srotas (Srotodushti) forms the fundamental basis of disease manifestation. Srotodushti arises due to improper diet, faulty lifestyle, suppression of natural urges, and psychological stress. These factors lead to Agnimandya (impaired digestive fire), Ama formation, Dosha vitiation, and obstruction or misdirection within bodily channels. Chronic diseases—whether metabolic, inflammatory, degenerative, or autoimmune—share a common underlying factor: persistent dysfunction of Srotas. Modern biomedical concepts such as microcirculatory impairment, chronic inflammation, endothelial dysfunction, and metabolic imbalance closely parallel the Ayurvedic concept of Srotodushti. Therefore, understanding this concept provides a comprehensive framework for explaining the origin and progression of chronic diseases. This article highlights the classical understanding of Srotas and Srotodushti, correlates it with modern pathophysiology, and emphasizes its importance in the prevention and management of chronic disorders through Nidana Parivarjana, Agni Deepana, and Srotoshodhana.
Jamre et al. (2026) studied this question.