Clinical and genetic characterization of intellectual disability | Synapse
March 21, 2026Open Access
Clinical and genetic characterization of intellectual disability
Key Points
The aim is to explore the clinical and genetic profiles associated with varying degrees of intellectual disability.
Assess the prevalence of somatic comorbidities in individuals with moderate to profound intellectual disability.
Evaluate the frequency of attention-deficit/hyperactivity disorder in those with mild intellectual disability.
Characterize genetic factors linked to different levels of intellectual disability.
Moderate to profound intellectual disability is associated with a higher frequency of somatic comorbidities.
Mild intellectual disability shows a notable increase in cases of attention-deficit/hyperactivity disorder.
Abstract
Somatic comorbidities were more common in moderate to profound intellectual disability, whereas attention-deficit/hyperactivity disorder was more frequent in mild intellectual disability.