Molecular epidemiological characterization of invasive extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae isolates from infants less than 3 months old in East Asia

Key Points

• The research aims to characterize the molecular epidemiology of antibiotic-resistant E. coli and K. pneumoniae in infants.
• Analyzed isolates from infants less than 3 months old in East Asia.
• Measured ceftriaxone resistance levels in bacterial samples.
• Identified predominant sequence types such as ST1193 and ST131.
• Ceftriaxone resistance was found in approximately 30% of isolates from Taiwan and over 60% from Korea.
• E. coli ST1193 and ST131 were the predominant strains identified.

Abstract