Global epidemiology of neonatal herpes: systematic review, meta-analyses, and meta-regressions | Synapse
March 22, 2026Open Access
Global epidemiology of neonatal herpes: systematic review, meta-analyses, and meta-regressions
Key Points
This research aims to analyze the global incidence and types of neonatal herpes in newborns.
Conducted systematic review of literature on neonatal herpes
Performed meta-analyses to quantify incidence
Utilized meta-regressions to identify regional variations and trends
nHSV affects approximately one in 10,000 newborns
Identified increasing incidence rates over time
nHSV-1 is becoming more dominant compared to nHSV-2 in various regions
Abstract
nHSV affects approximately one in 10 000 newborns, with regional variations and a rising incidence rate. The increasing dominance of nHSV-1 over nHSV-2 reflects shifting HSV epidemiology.