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July 20, 2018Journal of Biomechanical EngineeringOpen Access

The mean difference in peak strain across all sectors following repeat imaging was -0.1±2.3%, with a mean absolute difference of 1.7%, and mean homogenized peak strain by DENSE was consistent with SSFP cine estimates.

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Why the study?

Can 2D spiral cine DENSE MRI quantify regional circumferential Green strain in the thoracic and abdominal aorta in healthy volunteers?

Population

6 healthy volunteers (22-59 y.o., 4 females)

Comparison

Two-dimensional spiral cine displacement… vs Steady-state free procession cine MRI and repeat…

Design

Cross-sectional

Authors

JWJohn S. WilsonXZXiaodong ZhongJHJackson Hair

Discussion

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Overview

Demonstrates high repeatability of DENSE aortic strain in healthy volunteers; leaves clinical translation to aortopathies open.

Structured PICO

Can 2D spiral cine DENSE MRI quantify regional circumferential Green strain in the thoracic and abdominal aorta in healthy volunteers?

P
Population
6 healthy volunteers (22-59 y.o., 4 females)
I
Intervention
Two-dimensional (2D) spiral cine displacement encoding with stimulated echoes (DENSE) magnetic resonance imaging (MRI) at 3T
C
Comparator
Steady-state free procession (SSFP) cine MRI (for homogenized strain comparison) and repeat DENSE MRI (for interstudy repeatability)
O
Outcome
Regional displacement and circumferential Green strain of the thoracic and abdominal aortasurrogate

Aortic cine DENSE MRI is a viable noninvasive technique for quantifying heterogeneous regional aortic wall strain, offering potential for improved patient-specific assessment of aortopathies.

Cite This Study

Wilson et al. (2018) studied this question.

synapsesocial.com/papers/69c4314971099217f5a36ec3https://doi.org/10.1115/1.4040910
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