LUCAS-assisted mechanical CPR did not significantly improve 24-hour mortality (OR 1.54; 95% CI 0.94-2.53; p=0.09) or 60-day mortality versus manual CPR in overweight and obese IHCA patients.
Cohort (n=679)
Yes
Does LUCAS-assisted mechanical CPR improve 24-hour or 60-day mortality compared to manual CPR in overweight and obese patients with in-hospital cardiac arrest?
In overweight and obese patients experiencing in-hospital cardiac arrest, the use of LUCAS-assisted mechanical CPR does not significantly improve 24-hour or 60-day mortality compared to high-quality manual compressions.
Effect estimate: OR 1.54 (95% CI 0.94-2.53)
p-value: p=0.09
Introduction: Obesity is a growing global health concern that not only increases the risk of mortality but also complicates the clinical management of critically ill patients, particularly during cardiopulmonary resuscitation (CPR). This study aims to compare 24-hour and 60-day survival after in-hospital cardiac arrest (IHCA) in overweight (BMI ≥ 25 kg/m2) and obese patients (BMI ≥ 30 kg/m2) resuscitated with LUCAS assisted versus manual CPR, and to determine whether BMI (body mass index) modifies this association. Methods: Multicenter retrospective cohort of adult IHCA events at seven Mayo Clinic hospitals from January 2019 to January 2025. Cardiac arrests 0.14), indicating consistent effects across the BMI spectrum. Conclusions: In overweight and obese IHCA patients, LUCAS-assisted mechanical CPR did not improve 24-hour or 60-day mortality versus high quality manual compressions, and effectiveness was independent of BMI.
Pathak et al. (Sun,) conducted a cohort in In-hospital cardiac arrest in overweight and obese patients (n=679). LUCAS assisted CPR vs. Manual CPR was evaluated on 24-hour mortality (OR 1.54, 95% CI 0.94-2.53, p=0.09). LUCAS-assisted mechanical CPR did not significantly improve 24-hour mortality (OR 1.54; 95% CI 0.94-2.53; p=0.09) or 60-day mortality versus manual CPR in overweight and obese IHCA patients.