Introduction: The lungs possess extensive endothelium, serving as a critical window organ reflecting disease severity and therapeutic response. Lung ultrasound (LUS) captures pulmonary pathophysiological alterations, with distinct phenotypes correlating with disease profiles and time course manifestations. As shock represents the final pathway to mortality, dynamic LUS phenotype changes may reveal prognostic associations.We hope to investigate associations between longitudinal LUS phenotype evolution (assessed over 72hrs) and 30-day mortality in shock. Methods: 422 shock patients were enrolled (excluded: missing baseline data/observation0.05 all). This suggests late-stage LUS phenotype evolution, particularly posterior-consolidation patterns within preserved anterior zones, may reflect compensatory adaptations conferring survival advantage in shock. Conclusions: LUS phenotypes exhibit dynamic evolution with distinct transition patterns. D3-Class3 independently predicts reduced mortality, highlighting late-stage LUS phenotyping as a prognostic tool in shock.
Zeng et al. (Sun,) studied this question.