Survival Impact of Intraoperative Carbon Dioxide Dysregulation in Patients Undergoing Pancreaticoduodenectomy for Pancreatic Ductal Adenocarcinoma

Key Points

• To determine the relationship between intraoperative ETCO2 levels and oncologic outcomes in patients undergoing pancreaticoduodenectomy for pancreatic ductal adenocarcinoma.
• Assess mean intraoperative ETCO2 levels.
• Analyze the association between ETCO2 extremes and disease progression.
• Evaluate implications for patient selection and clinical decision-making.
• Mean ETCO2 identified as a strong marker of oncologic outcomes.
• Both high and low ETCO2 levels were linked to worse disease progression.
• Findings indicate potential improvements in patient care strategies.