What question did this study set out to answer?

This research aims to assess the predictive value of the second-trimester sFlt-1/PlGF ratio for adverse neonatal outcomes in patients with preeclampsia.

March 28, 2026Open Access

Association between second-trimester sFlt-1/PlGF ratio and composite adverse neonatal outcome in patients with preeclampsia

Key Points

This research aims to assess the predictive value of the second-trimester sFlt-1/PlGF ratio for adverse neonatal outcomes in patients with preeclampsia.
Observational study design
Assessment of sFlt-1 and PlGF levels in second trimester
Evaluation of neonatal outcomes in preeclampsia cases
sFlt-1/PlGF ratio is an independent predictor of composite adverse neonatal outcomes
High-risk neonates can be identified early using this biomarker
The predictive model informs personalized perinatal management strategies.

Abstract

The second-trimester sFlt-1/PlGF ratio is an independent predictor for CANO in PE. A model incorporating this biomarker facilitates the early identification of high-risk neonates, informing personalized perinatal management.

Association between second-trimester sFlt-1/PlGF ratio and composite adverse neonatal outcome in patients with preeclampsia

Key Points

Abstract

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