What does this research mean for the field?

Schizophrenia patients exhibit higher levels of eGFRcys12 and lower levels of mean eGFR and eGFRcc, demonstrating heterogeneity in the temporal sensitivity of kidney biomarkers that necessitates tailored monitoring approaches. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

This research aims to investigate kidney function biomarker changes in individuals with schizophrenia over a 14-year period.

March 28, 2026

Kidney Function Biomarkers and Longitudinal Changes in Schizophrenia: Evidence From a 14‐Year Health Checkup Cohort in Western China

Key Points

This research aims to investigate kidney function biomarker changes in individuals with schizophrenia over a 14-year period.
Analyzed longitudinal health checkup data from a cohort in Western China.
Measured kidney function using biomarkers like eGFRcys12, eGFR, and eGFRcc.
Assessed changes in kidney function over the study duration.
Schizophrenia patients exhibited higher eGFRcys12 levels.
Patients showed lower mean eGFR and eGFRcc values.
Variability in kidney biomarker sensitivity highlights the need for personalized monitoring strategies.

Abstract

Schizophrenia patients tend to exhibit higher levels of eGFRcys12 and lower levels of mean eGFR and eGFRcc. Heterogeneity in the temporal sensitivity of kidney biomarkers suggests the need for tailored approaches to kidney disease monitoring in this population.

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Kidney Function Biomarkers and Longitudinal Changes in Schizophrenia: Evidence From a 14‐Year Health Checkup Cohort in Western China

Key Points

Abstract

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