Objectives: This randomized clinical trial evaluated the effect of platelet-rich fibrin, simvastatin gel with platelet-rich fibrin, and alloplast with platelet-rich fibrin on implant stability and esthetic outcomes following immediate implant placement. Methods: Thirty-six patients requiring maxillary anterior immediate implants were randomized into three groups. Clinical and radiographic parameters including implant stability quotient, labial bone thickness, marginal bone level, pink esthetic score, and patient satisfaction were assessed up to one year. Results: Implant stability and pink esthetic scores showed no statistically significant intergroup differences. All groups demonstrated improved esthetic outcomes over time. Alloplast combined with platelet-rich fibrin exhibited the most stable peri-implant soft tissue parameters. Conclusions: All evaluated grafting protocols produced favorable clinical and esthetic outcomes. Alloplast demonstrated superior peri-implant tissue stability over time.
Pruthi et al. (Sun,) studied this question.