Comparison of the effects of intrathecal hyperbaric bupivacaine, levobupivacaine, and ropivacaine during interventional brachytherapy: A double-blind, randomized crossover study

Key Points

• The study aims to compare the effectiveness and safety of three local anesthetics for spinal anesthesia during brachytherapy.
• Conducted as a double-blind, randomized crossover study
• Compared three intrathecal agents: bupivacaine, levobupivacaine, and ropivacaine
• Evaluated sensory and motor block duration and cardiovascular effects.
• Ropivacaine provided the shortest sensory and motor blocks.
• Levobupivacaine showed the most stable cardiovascular profile.
• Bupivacaine resulted in the longest blocks but increased rates of hypotension and tachycardia.