What question did this study set out to answer?

To highlight Bundgaard syndrome as a rare but significant cause of persistent diffuse ST-segment depression.

April 5, 2026Open Access

Bundgaard Syndrome as a Rare Cause of Diffuse ST-Segment Depression

Key Result

Bundgaard syndrome is a rare cause of persistent, widespread ST-segment depression without ischemia and can serve as a precursor to malignant arrhythmias.

Key Points

To highlight Bundgaard syndrome as a rare but significant cause of persistent diffuse ST-segment depression.
Review of clinical cases exhibiting diffuse ST-segment depression
Analysis of arrhythmias linked to Bundgaard syndrome
Assessment of symptoms in the absence of ischemic indications
Bundgaard syndrome identified in cases with unexplained ST-segment depression
Patients showed predisposition to malignant arrhythmias
Nonspecific ST-segment changes observed without signs of ischemia

Structured PICO

Population

Patients with persistent widespread ST-segment depression without ischemia

Bundgaard syndrome should be considered in the differential diagnosis of persistent widespread ST-segment depression without ischemia due to its risk of malignant arrhythmias.

Main Result

Absolute Event Rate: 0% vs 0%

Abstract

Bundgaard syndrome, which can be a precursor to malignant arrhythmias, should be kept in mind in patients with persistent widespread ST-segment depression without ischemia.

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Cite This Study

Ekinci et al. (Wed,) reported a other. Bundgaard syndrome is a rare cause of persistent, widespread ST-segment depression without ischemia and can serve as a precursor to malignant arrhythmias.

synapsesocial.com/papers/69d1fdbfa79560c99a0a4008 https://doi.org/https://doi.org/10.1016/j.jaccas.2026.107607

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