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November 4, 2010ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam)350 citations

Radiofrequency ablation for persistent atrial fibrillation in patients with advanced heart failure and severe left ventricular systolic dysfunction: a randomised controlled trial

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MMMichael R. MacDonaldDCDerek T. ConnellyNHNathaniel M. Hawkins

Structured PICO

Does radiofrequency ablation improve CMR LVEF compared to a rate control strategy in patients with persistent atrial fibrillation and advanced heart failure?

P
Population
Patients with persistent atrial fibrillation, advanced heart failure, and severe left ventricular systolic dysfunction
I
Intervention
Radiofrequency ablation (RFA)
C
Comparator
Strategy of rate control
O
Outcome
Left ventricular ejection fraction (LVEF) measured by cardiac magnetic resonance (CMR)surrogate

In patients with persistent atrial fibrillation and advanced heart failure, radiofrequency ablation did not improve CMR LVEF compared to rate control and was associated with significant serious complications.

Abstract

RFA resulted in long-term restoration of sinus rhythm in only 50% of patients. RFA did not improve CMR LVEF compared with a strategy of rate control. RFA did improve radionuclide LVEF but did not improve other secondary outcomes and was associated with a significant rate of serious complications.

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Cite This Study

MacDonald et al. (2010) studied this question.

synapsesocial.com/papers/69d56c3d75589c71d767cd13https://doi.org/10.1136/hrt.2010.207340
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