August 8, 2014Open Access

Promoter methylation analysis of WNT/β-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer

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Abstract

The rate of gene promoter methylation of WNT pathway regulators is high in colorectal cancer cells. Hyper-methylation is associated with increased expression of the DNMT1 enzyme.

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Samaei et al. (Fri,) studied this question.

synapsesocial.com/papers/69d56e2f75589c71d767d4b0 https://doi.org/https://doi.org/10.1186/s12929-014-0073-3

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5Promoter methylation of the Wnt/β‐catenin signaling antagonist <i>Dkk‐3</i> is associated with poor survival in gastric cancer2008 · 129 citations

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