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February 22, 2011Circulation334 citationsOpen Access

Diabetes and Antiplatelet Therapy in Acute Coronary Syndrome

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JFJosé Luis FerreiroDADominick J. Angiolillo

Structured PICO

P
Population
Patients with diabetes mellitus (DM) and acute coronary syndromes (ACS), including unstable angina, NSTEMI, and STEMI.
I
Intervention
Antiplatelet therapy

Diabetes mellitus is a strong independent predictor of recurrent ischemic events and mortality across the spectrum of acute coronary syndromes.

Abstract

C ardiovascular disease, particularly coronary artery dis- ease resulting from accelerated atherosclerosis, is the leading cause of morbidity and mortality in patients with diabetes mellitus (DM). In fact, in the setting of acute coronary syndromes (ACS), the presence of DM is a strong independent predictor of short-term and long-term recurrent ischemic events, including mortality. he concomitant presence of cardiovascular risk factors and comorbidities that negatively affect the outcomes of ACS is higher in DM patients. The negative impact of DM on outcomes is maintained across the ACS spectrum, including unstable angina and non-ST-elevation MI (NSTEMI), 7 STelevation MI (STEMI) treated medically, 8 and ACS undergoing percutaneous coronary intervention (PCI). 2]

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Cite This Study

Ferreiro et al. (2011) studied this question.

synapsesocial.com/papers/69d570aa75589c71d767de1chttps://doi.org/10.1161/circulationaha.109.913376
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