Does the Index of Cardio-Electrophysiological Balance (iCEB) identify patients at increased arrhythmic risk?
The Index of Cardio-Electrophysiological Balance (iCEB, calculated as QT/QRS) may serve as a simple, noninvasive ECG biomarker to identify patients at risk for different types of ventricular arrhythmias.
Our data suggest that iCEB (QT/QRS) is a simple but effective ECG surrogate of cardiac wavelength. iCEB is increased in situations that predispose to TdP and is decreased in situations that predispose to non-TdP mediated VT/VF. Therefore, iCEB might serve as a noninvasive and readily measurable marker to detect increased arrhythmic risk.
Robyns et al. (2015) studied this question.