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July 15, 2012Antioxidants and Redox Signaling329 citations

Oxidative Stress, Redox Signaling, and Metal Chelation in Anthracycline Cardiotoxicity and Pharmacological Cardioprotection

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MŠMartin ŠtěrbaCardio-OncologyOPOlga PopelováCharles UniversityAVAnna VávrováInstitute of Applied Geophysics of the Academy of Sciences

Structured PICO

I
Intervention
Dexrazoxane

Dexrazoxane warrants further investigation for its cardioprotective action against anthracycline cardiotoxicity beyond simple iron chelation.

Abstract

Dexrazoxane may be the key to the enigma of anthracycline cardiotoxicity, and therefore it warrants further investigation, including the search for alternative/complementary modes of cardioprotective action beyond simple iron chelation.

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Cite This Study

Štěrba et al. (2012) studied this question.

synapsesocial.com/papers/69d572d475589c71d767e825https://doi.org/10.1089/ars.2012.4795
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