Hypomagnesemia Associated with Omeprazole Use in Patients Treated with Platinum Derivatives: An Exploratory Randomized Placebo-Controlled Clinical Trial.

Key Result

Omeprazole use is associated with hypomagnesemia in patients treated with platinum derivatives.

Key Points

• This research investigates the connection between omeprazole use and hypomagnesemia in patients treated with platinum derivatives.
• Conducted a randomized placebo-controlled trial
• Included patients receiving platinum derivatives
• Compared magnesium levels between omeprazole and placebo groups
• Observed a significant incidence of hypomagnesemia in the omeprazole group
• Indicated a potential risk of magnesium deficiency associated with omeprazole use