Adverse drug reactions (ADRs) pose a significant challenge to patient safety, particularly in high-acuity settings such as emergency departments. Despite their critical role in pharmacovigilance, nurses often underreport ADRs due to systemic, knowledge-related, and attitudinal barriers. This study assessed nurses’ knowledge, attitudes and barriers toward ADR reporting in the Accident and Emergency (A yet, only 32.3% were able to articulate institutional reporting protocols. Although 89% recognised the significance of ADR reporting, only 24% consistently recorded ADRs. Significant obstacles included insufficient time (78.6%), poor training (63.2%), fear of retribution (58.1%), convoluted forms (49.3%), and hierarchical conventions (44.1%). The intention to report emerged as the most significant predictor (B = 0.52, β = 0.538, p < .001), whereas attitudes (B = 0.314, p < .001) and perceived behavioural control (B = 0.352, p < .001) somewhat mediated the influence of knowledge (B = 0.198, p = .008) on ADR reporting. Although the respondents possessed adequate knowledge of ADRs, this knowledge does not consistently translate into reported practices. Again, despite their favorable attitudes toward the value of ADR reporting, systemic and cultural barriers which included workflow constraints, fear of professional repercussions inhibited their active participation. Implementing context-specific training, introducing streamlined electronic reporting tools, establishing feedback mechanisms, and fostering leadership support is critical to enhancing ADR reporting. Not applicable.
Sagoe et al. (Mon,) studied this question.