August 12, 2022Open Access

miR-22 alleviates sepsis-induced acute kidney injury via targeting the HMGB1/TLR4/NF-κB signaling pathway

JZJie ZhangHeilongjiang University of Chinese Medicine QCQi ChenGuangxi Medical University ZDZhuquan DaiHuzhou University

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Abstract

miR-22 can inhibit the inflammatory response, target the HMGB1, and inhibit the HMGB1/TLR4/NF-kB pathway, to attenuate the sepsis-induced AKI, which indicates that miR-22 may serve as a potential treatment target in sepsis-induced AKI.

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