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February 9, 2012Journal of Nuclear Medicine224 citationsOpen Access

Clinical Validation of 18F-AZD4694, an Amyloid-β–Specific PET Radioligand

ZCZsolt CselényiMEMaria EriksdotterAFAnton Forsberg

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Abstract

Noninvasive quantitative approaches provide valid estimates of amyloid-β binding. Because of the radioisotope ((18)F) used for labeling, the radioligand has potential for wide clinical application. (18)F-AZD4694 satisfies the requirements for a promising amyloid-β radioligand both for diagnostic use and for evaluation of disease-modifying therapies in AD.

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Cselényi et al. (2012) studied this question.

synapsesocial.com/papers/69d740c1b4cef8fedc48f4d1https://doi.org/10.2967/jnumed.111.094029
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