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March 1, 2023Drug Design Development and Therapy85 citationsOpen Access

Effect of Subanesthetic Dose of Esketamine on Perioperative Neurocognitive Disorders in Elderly Undergoing Gastrointestinal Surgery: A Randomized Controlled Trial

CHChao HanHJHaiyan JiYGYaxin Guo

Structured PICO

Does sub-anesthetic dose of esketamine reduce the incidence of dNCR and improve early postoperative cognitive function in elderly patients undergoing gastrointestinal surgery?

P
Population
Elderly patients undergoing gastrointestinal surgery
I
Intervention
Sub-anesthetic doses of esketamine
O
Outcome
Incidence of delayed neurocognitive recovery (dNCR) and early postoperative cognitive function

Sub-anesthetic esketamine may reduce delayed neurocognitive recovery and improve early postoperative cognitive function in elderly patients undergoing gastrointestinal surgery.

Abstract

Sub-anesthetic doses of esketamine might reduce the incidence of dNCR and improve early postoperative cognitive function in elderly patients undergoing gastrointestinal surgery, which might be related to the anti-neuroinflammation effects of esketamine.

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Cite This Study

Han et al. (2023) studied this question.

synapsesocial.com/papers/69d83b2152654bb436d18c79https://doi.org/10.2147/dddt.s401161
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