Longitudinal blood pressure trajectories and tau‐lipid biomarkers associated with dementia in hypertensive adults: Results from the population‐based CRHCP cohort

Key Points

• The study aims to explore how different blood pressure trajectories relate to dementia in adults with hypertension.
• Analyzed longitudinal blood pressure data from the CRHCP cohort.
• Examined the association of blood pressure trajectories with dementia incidence.
• Considered tau-lipid biomarkers, particularly pTau217-lipid composite indices.
• High-stable blood pressure trajectories were consistently linked to increased dementia risk.
• Associations between high-declining and moderate-stable blood pressure trajectories varied depending on tau-lipid biomarker levels.

Structured PICO

Abstract