Supramolecular masks for the regioselective synthesis of Diels-Alder hetero-tris-adduct C60 fullerene

Key Points

• The aim is to develop a method for regioselective functionalization of C60 fullerenes using a Diels-Alder approach.
• Utilized supramolecular masks to direct the functionalization of C60.
• Applied Ru-catalyzed cycloisomerization to introduce the first addend.
• Executed sequential Diels-Alder cycloaddition for complete functionalization.
• Successfully achieved regioselective hetero-tris-functionalization of C60 fullerenes.
• Confirmed the efficacy of the synthetic strategy with high yields in the Diels-Alder process.