Molecular Engineering of Functional Nucleic Acids for Detection of Biological Contaminants

Key Points

• The aim is to explore the use of functional nucleic acids for the rapid and accurate detection of biological contaminants.
• Reviewed strategies for in vitro selection of functional nucleic acids.
• Discussed library design for nucleic acid functions.
• Examined engineering approaches for molecular assembly.
• Classified biosensors developed using functional nucleic acids for detection of contaminants.
• Functional nucleic acids show potential for broad target recognition and easy synthesis.
• Highlighted applications in both optical and electrochemical biosensors.
• Demonstrated improved detection methods over traditional techniques.

Abstract