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August 19, 2008Angewandte Chemie International Edition890 citationsOpen Access

Hydrolytic Stability of Hydrazones and Oximes

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JKJeet KaliaIndian Institute of Science Education and Research, BhopalRRRonald T. RainesBoston College

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Abstract

Watching C 'n' N: Hydrazones and oximes are common conjugates but are labile to hydrolysis. The hydrolytic stabilities of isostructural hydrazones and one oxime were determined at pD 5. 0–9. 0. The rate constant for the acid-catalyzed hydrolysis of the oxime was nearly 103-fold lower than those for simple hydrazones, and a trialkylhydrazonium ion (formed after condensation) was even more stable than the oxime. Supporting information for this article is available on the WWW under http: //www. wiley-vch. de/contents/jc₂002/2008/z802651ₛ. pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

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Cite This Study

Kalia et al. (2008) studied this question.

synapsesocial.com/papers/69d8f314e72b319804d17d0bhttps://doi.org/10.1002/anie.200802651
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